2008 Ekim ayinda Roma'da yapilan Avrupa Diyabet Kongresi'nde sunulan calismalarda benfotiamin vitamininin retinopati (goz hasari) ve bobrek hasarindan seker hastalarini korudugu bildirildi. Benfotiamin ulkemizde satilmiyor, Almanya da Milgamma 100 adiyla satiliyor. ABD de ise LEF firmasi ve baska firmalar benfotiamin adiyla satiyorlar.
Diabetologia dergisinde yayinlanan calismada benfotiaminin böbrek hasarindan korudugu saptanmis.
''Recent study results suggest that taking a high-dose vitamin B1 supplement each day may help diabetics reduce their risk of kidney damage.
Diabetic nephropathy, or kidney disease, is a common complication of type 2 diabetes. An early indicator of kidney disease is microalbuminuria, where the kidney leaks albumin into the urine. Researchers set out to investigate whether supplementation with vitamin B1 would effect microalbuminuria.
Type 2 diabetics were given 300 milligrams of vitamin B1 (thiamine) each day for three months. Results showed that the vitamin supplement reduced the rate of albumin excretion by 41%. Furthermore, 35% of patients with microalbuminuria saw their urine albumin excretion return to normal after being treated with the vitamin. Thus, suggesting that treatment with high-dose vitamin B1 can reverse the onset of early diabetic kidney disease.
Rabbani N, Alam SS, Riaz S, Larkin JR, Akhtar MW, Shaf T, Thornalley PJ. High-dose thiamine therapy for patients with type 2 diabetes and microalbuminuria: a randomised, double-blind placebo-controlled pilot study. Diabetologia. Published online December 5th 2008. doi: 10.1007/s00125-008-1224-4''